As far as I know the main difference here is in speed, and some of that may be wasted here. I don't think the D5100 can utilize any speed faster than UHS-1 or class 10 so I would not pay extra for higher speeds than it can use. I have noted that some cards seem to be faster than others of the same rating, but sometimes it seems that a fast UHS-1 works better than a UHS-2, and it's hard to sort them out except by luck.
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